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Best allergy medicines - August 2025

Last Updated - August 29, 2025

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Claritin

Claritin Allergy Medicine for Adults, 24-Hour Non-Drowsy Loratadine 10mg Pills, Antihistamine, 100 Tablets

Claritin

$49.97

More Details
Main highlights
- TRUSTED BRAND: #1 doctor recommended non-drowsy oral OTC allergy brand
- POWERFUL, 24 HOUR INDOOR AND OUTDOOR ALLERGY PILLS: Relief of your worst allergy symptoms including sneezing, runny nose, itchy watery eyes, and itchy throat or nose
- NO PRESCRIPTION NEEDED: Find relief of allergy symptoms triggered by over 200 indoor and outdoor allergens from pets, pollen, dust and mold*
- INDICATED FOR AGES 6 YEARS AND OLDER: Prescription strength, allergy relief that lasts all-day
- HSA/FSA ELIGIBLE: Check your plan for coverage
- 100 DAYS OF 24 HOUR NON-DROWSY ALLERGY RELIEF: Claritin contains 10 milligrams of loratadine per tablet, that blocks the effects of histamines in the body
- *Claritin is an antihistamine so it hinders the cascade triggered by allergens
$49.97
2
23% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Xyzal
23% Off

Xyzal 24 Hour Allergy Relief Medicine, Original Prescription Strength Antihistamine, Levocetirizine Dihydrochloride Tablets, 5 mg, 80 Count

Xyzal

$29.04

$37.99
(23% Off)

More Details
Main highlights
- LONG LASTING: Rapid relief* that's as effective at hour 24 as it is at hour one *Starts working in 45 minutes
- INDOOR AND OUTDOOR ALLERGY RELIEF: Prescription strength relief from outdoor and indoor allergens including pollen, ragweed, grass, trees, dust, mold and pet dander
- CONTINUOUS RELIEF: Continuously relieves itchy, watery eyes caused by allergies
- CONTAINS: One (1) 80-count bottle of Xyzal 24 Hour Allergy Relief Medicine, Original Prescription Strength Antihistamine, Levocetirizine Dihydrochloride Tablets, 5 mg
- ALLERGY SYMPTOM RELIEF:Fights allergy symptoms including sneezing; itchy, watery eyes; runny nose; itchy nose or throat
- ALL DAY ALLERGY RELIEF: Take Xyzal at night for relief while you sleep and all the next day
- ACTIVE INGREDIENT: Effective antihistamine with active ingredient levocetirizine dihydrochloride
$29.04
$37.99 (23% Off)
3
Best Value
24% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Benadryl
24% Off

Benadryl Ultratabs Allergy Relief Medicine, 25 mg Diphenhydramine HCl Antihistamine Tablets For Relief of Cold & Allergy Symptoms Like Sneezing, Runny Nose, & Itchy Eyes & Throat, 100 ct

Benadryl

$14.88

$19.74
(24% Off)

More Details
Main highlights
- POWERFUL ALLERGY & COLD RELIEF IN JUST 1 PILL: Adults & children 12+, take one to two allergy tablets every four to six hours. Children ages 6-12, take one allergy medicine tablet every four to six hours. Do not give more than six doses in 24 hours
- DIPHENHYDRAMINE HCl FORMULA: Benadryl allergy medicine is formulated with 25 mg of diphenhydramine hydrochloride, an antihistamine that works to help provide allergy and upper respiratory relief
- COLD SYMPTOM RELIEF: The antihistamine tablets with diphenhydramine hydrochloride feature an effective and powerful formula that works when you need it most. The tablets for multi-symptom relief help tackle both cold and allergy symptoms
- ANTIHISTAMINE TABLETS: This allergy medicine temporarily provides relief of hay fever and other upper respiratory symptoms such as sneezing and runny nose. It also provides relief from common allergens such as tree pollen, dust, mold and pet dander
- ALLERGY RELIEF MEDICATION: 100-count package of Benadryl Allergy Tablets for allergy relief help to alleviate symptoms associated with allergies such as sneezing, runny nose, itchy throat or nose, and itchy/watery eyes
$14.88
$19.74 (24% Off)
4
23% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Xyzal
23% Off

Xyzal 24 Hour Allergy Relief Medicine, Original Prescription Strength Antihistamine, Levocetirizine Dihydrochloride Tablets, 5 mg, 35 Count

Xyzal

$13.65

$17.96
(23% Off)

More Details
Main highlights
- LONG LASTING: Rapid relief* that's as effective at hour 24 as it is at hour one *Starts working in 45 minutes
- INDOOR AND OUTDOOR ALLERGY RELIEF: Prescription strength relief from outdoor and indoor allergens including pollen, ragweed, grass, trees, dust, mold and pet dander
- CONTINUOUS RELIEF: Continuously relieves itchy, watery eyes caused by allergies
- CONTAINS: One (1) 35-count bottle of Xyzal 24 Hour Allergy Relief Medicine, Original Prescription Strength Antihistamine, Levocetirizine Dihydrochloride Tablets, 5 mg
- ALLERGY SYMPTOM RELIEF: Fights allergy symptoms including sneezing; itchy, watery eyes; runny nose; itchy nose or throat
- ALL DAY ALLERGY RELIEF: Take Xyzal at night for relief while you sleep and all the next day
- ACTIVE INGREDIENT: Effective antihistamine with active ingredient levocetirizine dihydrochloride
$13.65
$17.96 (23% Off)
5

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

GoodSense

GoodSense All Day Allergy, Cetirizine Hydrochloride Tablets, 10 mg, Antihistamine, 365 Count

GoodSense

$16.99

More Details
Main highlights
- UNDERSTANDING ALLERGIES: An allergy is a sensitivity to a substance that is normally harmless. Flowers, trees, a family pet, or dust are examples of things that can cause an allergy. These allergy pills provide up to 24 hours of temporary relief
- INDOOR AND OUTDOOR ALLERGY RELIEF: Temporarily relieves common indoor and outdoor allergy symptoms
- EFFECTIVE: GoodSense All Day Allergy, Cetirizine Hydrochloride Tablets, 10 mg are original prescription strength and gluten free. These allergy pills are an antihistamine approved for the treatment of both indoor and outdoor allergy symptoms
- ACTIVE INGREDIENT: The active ingredient in GoodSense All Day Allergy is cetirizine hydrochloride, an antihistamine approved for the treatment of both indoor and outdoor allergy symptoms. Compare to the active ingredient of Zyrtec
- 24-HOUR ALLERGY RELIEF: Temporarily provides relief of symptoms due to hay fever or other upper respiratory allergies: runny nose, sneezing, itching of the nose or throat and itchy, watery eyes
$16.99

Best allergy medicines - August 2025

Claritin Allergy Medicine for Adults, 24-Hour Non-Drowsy Loratadine 10mg Pills, Antihistamine, 100 Tablets

Xyzal 24 Hour Allergy Relief Medicine, Original Prescription Strength Antihistamine, Levocetirizine Dihydrochloride Tablets, 5 mg, 80 Count

Benadryl Ultratabs Allergy Relief Medicine, 25 mg Diphenhydramine HCl Antihistamine Tablets For Relief of Cold & Allergy Symptoms Like Sneezing, Runny Nose, & Itchy Eyes & Throat, 100 ct

Xyzal 24 Hour Allergy Relief Medicine, Original Prescription Strength Antihistamine, Levocetirizine Dihydrochloride Tablets, 5 mg, 35 Count

GoodSense All Day Allergy, Cetirizine Hydrochloride Tablets, 10 mg, Antihistamine, 365 Count

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