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Best over counter medications - August 2025

Last Updated - August 28, 2025

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Jelcaine Sterile

Lidocaine Jelly 2% Numbing Gel for Burn Relief 30ml - Sunburn Relief with Lidocaine, Topical for Pain, Minor Cuts, Skin Irritation, Insect Bites, Sensitive Area, Anesthetic Over-the-Counter Medication

Jelcaine Sterile

$22.49

More Details
Main highlights
- TARGETED APPLICATION WITH PRECISION CONE: Our topical anesthetic sterile precision cone allows for accurate application of Jelcaine Sterile to the affected area. Ideal for sunburn relief, minor burns, or itchy skin, the precision cone ensures focused relief where you need it most including sensitive, intimate and discreet areas including use a topical, vaginal Lidocaine gel. . Jelcaine topical anesthetic gel also works well for providing pain relief to sensitive areas of your body.
- QUALITY STERILE AND SAFE PACKAGING: Jelcaine Sterile comes in a 30ml tube pre-packaged in a sealed, sterile pouch, ensuring hygiene and safety with every use. Our sterilized packaging is great for those seeking sunburn relief in sterile burn gel packets to relieve pain. Whether using topical lidocaine for sensitive skin areas or burn relief, you can be confident in a safe, clean application each time.
- INSTANT AND MULTIPLE PAIN RELIEF USES: Jelcaine Sterile topical pain relief solution offers quick alleviation and numbing for numerous pain and itch-related problems. It temporarily relieves discomfort from minor cuts, sunburn, minor scrapes, minor burns, insect bites, and skin irritations. It provides intimate pain relief for sensitive areas. Our lidocaine gel is odor-free, cooling, unscented, greaseless, and water-soluble, offering smooth, moisturizing application without sticky residue.
- FAST AND EFFECTIVE PAIN RELIEF WITH LIDOCAINE GEL: Jelcaine Sterile is a powerful lidocaine gel, offering fast and effective pain relief for cuts, scrapes, insect bites, sunburn, or other skin irritations. Whether you need burn relief gel for a recent burn or a numbing gel for itchy, irritated skin, Jelcaine works quickly to reduce discomfort, helping you get back to your day. An essential addition to your medicine cabinet, including burn gel and burn dressing.
- CONVENIENT, PORTABLE, AND HSA/FSA ELIGIBLE: Our 30ml tube of Jelcaine Sterile offers a convenient and portable solution for ongoing pain relief. Ideal for home use or on-the-go, it provides a cost-effective, versatile and reliable option for sunburn relief, minor burn care, and itchy skin relief. Plus, it’s eligible for HSA and FSA purchases, helping you save while stocking up on this essential pain relief product. OTC products eligible without a prescription.
$22.49
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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Opill

Opill, Daily Oral Birth Control Pills, Over-The-Counter Progestin-Only Contraceptive, FDA-Approved & Estrogen-Free, 28 Count

Opill

$18.97

$19.99
(5% Off)

More Details
Main highlights
- PROGESTIN-ONLY: Opill is progestin-only and can be taken by most* people who can get pregnant. *Do not use Opill if you have or ever had breast cancer. See Opill label for list of warnings.
- OTC BIRTH CONTROL PILL: Opill is the first over the counter, daily oral contraceptive pill that is available without a prescription. No prescription. No appointment. No hassle.
- FULL PRESCRIPTION STRENGTH: Opill is the most effective over-the-counter contraceptive available for people who can become pregnant when used as directed.
- FDA-APPROVED: Opill is the first prescription-free, daily birth control pill approved by the FDA for over-the-counter use, adding convenience and increasing accessibility for those who need it most.
- 98% EFFECTIVE: Our estrogen-free, daily contraceptive pill is 98% effective at preventing pregnancy when taken as directed at the same time every day, providing birth control in your control.
$18.97
$19.99 (5% Off)
3
Best Value
16% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Motrin
16% Off

Motrin IB Ibuprofen 200mg Tablets, Ibuprofen Pain & Fever Reliever for Headache, Backache, Muscular Aches, Menstrual Pain & Minor Arthritis Pain, Over-The-Counter NSAID Medicine, 225 ct

Motrin

$16.97

$20.24
(16% Off)

More Details
Main highlights
- Motrin IB ibuprofen tablets temporarily reduce fever and offer pain relief due to the common cold, minor pain of arthritis, headache, backache, toothache and menstrual cramps
- Motrin IB ibuprofen tablets are indicated for ages 12 years or older and are safe and effective when used as directed for fever and pain relief
- Get long-lasting pain relief with Motrin IB ibuprofen tablets. Adults and children 12 years and older, take one pain relief caplet every four to six hours while symptoms persist. If pain or fever does not respond, two caplets may be used
- Each Motrin IB tablet contains 200 milligrams of fast-acting ibuprofen pain relief medicine to help stop pain at its source and provide powerful pain relief when it counts
- 225-count bottle of Motrin IB tablets with the NSAID ibuprofen pain reliever offer fast acting & effective pain relief from minor aches and pains
$16.97
$20.24 (16% Off)
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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Mucinex

Mucinex Fast-Max Maximum Strength Day & Night Cold and Flu Medicine for Adults, Powerful Over-The-Counter Medication for Cold & Flu Symptoms, Fast Release Caplets, 20 Count

Mucinex

$13.99

More Details
Main highlights
- RUNNY NOSE RELIEF: Triprolidine HCl helps relieve runny nose, sneezing, itchy throat, & itchy/watery eyes (nighttime caplets only)
- PAIN & FEVER RELIEF: Acetaminophen helps reduce fever and relieve pain like headache, body aches, sore throat including those associated with cold & flu
- NOTHING WORKS FASTER**: Fast-release caplets for powerful multi-symptom cold and flu relief day and night
- FLU MEDICINE FOR ADULTS: Mucinex Fast-Max Daytime Cold & Flu & Nighttime Cold & Flu Caplets provides multi-symptom relief for your worst symptoms day and night
- COUGH SUPPRESSANT: Contains Dextromethorpan HBr which helps suppress the urge to cough during the day and at night to help you get to sleep
- COLD AND FLU MEDICINE: Mucinex Fast-Max Daytime Cold & Flu & Nighttime Cold & Flu Caplets give powerful relief for headache, sore throat, body pain, fever, cough, runny nose and more
- **Among oral OTC cold & flu caplets
- #1 TRUSTED COLD & COUGH BRAND: Mucinex is the #1 cough and cold brand doctors trust*
$13.99
5

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Sourcebooks

Over the Counter Natural Cures, Expanded Edition: Take Charge of Your Health in 30 Days with 10 Lifesaving Supplements for under $10 (Herbal Remedies and Alternative Medicine Book)

Sourcebooks

$17.07

$17.99
(5% Off)

More Details
Main highlights
- Used Book in Good Condition
$17.07
$17.99 (5% Off)

Best over counter medications - August 2025

Lidocaine Jelly 2% Numbing Gel for Burn Relief 30ml - Sunburn Relief with Lidocaine, Topical for Pain, Minor Cuts, Skin Irritation, Insect Bites, Sensitive Area, Anesthetic Over-the-Counter Medication

Opill, Daily Oral Birth Control Pills, Over-The-Counter Progestin-Only Contraceptive, FDA-Approved & Estrogen-Free, 28 Count

Motrin IB Ibuprofen 200mg Tablets, Ibuprofen Pain & Fever Reliever for Headache, Backache, Muscular Aches, Menstrual Pain & Minor Arthritis Pain, Over-The-Counter NSAID Medicine, 225 ct

Mucinex Fast-Max Maximum Strength Day & Night Cold and Flu Medicine for Adults, Powerful Over-The-Counter Medication for Cold & Flu Symptoms, Fast Release Caplets, 20 Count

Over the Counter Natural Cures, Expanded Edition: Take Charge of Your Health in 30 Days with 10 Lifesaving Supplements for under $10 (Herbal Remedies and Alternative Medicine Book)

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Mucinex Fast-Max Maximum Strength Cold, Flu & Sore Throat Medicine for Adults, Powerful Over-The-Counter Medication for Chest Congestion & Cold and Flu Symptoms, Fast Dissolving Liquid Gels, 16 Count

WELMATE - Levocetirizine Dihydrochloride 5mg (180 ct) - Non Drowsy Allergy Medicine - 24 Hours - Antihistamine - Generic Allergy Pills - Over-The-Counter Medication

Mucinex Fast-Max Maximum Strength Cold and Flu Medicine for Adults, Powerful Over-The-Counter Medication for 6 Different Cold & Flu Symptoms, Fast Release Caplets, 20 Count

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